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10 Best Mouse For Big Hands & Buying Guide

Mouse size is a personal preference, and there is no one-size-fits-all answer to the question of which mouse is best for big hands. Some people prefer large mice with a lot of buttons, while others find that small mice are more comfortable to use. Ultimately, the best mouse for big hands is the one that feels most comfortable in your hand.

Our Top Picks At A Glance

Take a look at the following comparison chart of our top 10 best mouse for big hands that will win your heart.

10 Best Mouse For Big Hands People Love In 2022: In Depth Features

Bestseller No. 1
Left-Handed Mouse, 2.4GHz Wireless Left Hand Ergonomic Vertical Mouse with USB Receiver, Sensitive and Quiet Click
  • Left-hand Ergonomic Vertical Mouse - A great ergonomic mouse for left-handers, encourage healthy natural “handshake” wrist/palm position for the most comfortable grip, less wrist strain. Recommended to repetitive strain injuries RSI users and people who work particularly long period on the computer. Mouse dimensions: 4.3*2.6*2.2 inches. 【Reminder: Please confirm the size before buying it. 】
  • Sensitive Click, Less Noise - 800/1200/1600 DPI level available, easy to change the cursor sensitivity by just pressing the DPI button,allows fast response, smooth tracking and precise movement. Quiet click with less noise, no disturbing others besides you. A superior choice for internet surfers, gamers and people working at the computer.
  • Advanced Functionality - Added side buttons for “Page Forward” /”Page Back” function provide big convenience when browsing web page. 【 NOTE: The vertical mouse can not fully compatible with Macbook, Mac os x operating system. The backward and forward browsing buttons will not work, and the scrolling is contrary to Mac. (Because Apple company product only support its own system) 】
  • Plug & Play - Just plug the included Nano receiver into the USB port of your computer, no other additional software needed. Provides a stable, powerful wireless connection up to 10m, very easy to use. 【Note: The USB receiver is stored in the battery compartment of the mouse and it needs a one AA 1.5V battery, not included in the package】
  • Great Compatibility - Compatible with most system including Windows 7 / 8 / 10, XP, Vista and Linux. Fit for Notebook, PC, Laptop, Computer, and other device. 【 Not fully compatible with Apple products】
Bestseller No. 2
Logitech Signature M650 L Full Size Wireless Mouse - for Large Sized Hands, 2-Year Battery, Silent Clicks, Customizable Side Buttons, Bluetooth, Multi-Device Compatibility - Black
  • Scroll smarter: With Logitech Signature M650 Wireless Mouse you get line-by-line precision for documents and super-fast scrolling for long web pages; simply switch modes with a flick of the SmartWheel
  • The optimal fit for your hand: This comfortable full size mouse is designed for larger hands, for the optimal fit
  • Upgrade your comfort: This work mouse provides long hours of comfort thanks to a contoured shape, soft thumb area, and rubber side grips that keep your hand snug and in place
  • Connect the way you like: Connect this cordless computer mouse in an instant via Bluetooth Low Energy or Logi Bolt USB receiver
  • Less noise, more focus: Whether working at the office or at home, Logitech Signature M650 is a quiet mouse, allowing you to enjoy 90 percent less click noise with SilentTouch technology*
SaleBestseller No. 3
Logitech M525 Wireless Mouse – Long 3 Year Battery Life, Ergonomic Shape for Right or Left Hand Use, Micro-Precision Scroll Wheel, and USB Unifying Receiver for Computers and Laptops, Black/Gray
  • ERGONOMIC SHAPE - Ergonomically shaped design and soft rubber grips conform to your hand to be naturally comfortable and the compact size makes it easy to take with you wherever you use your computer at home, at work or anywhere else, USB receiver is stored inside the mouse where the batteries are located
  • Interface: USB receiver. Mouse Dimensions (height x width x depth)-4.00 x 2.24 x 1.51 inches. Receiver Dimensions (height x width x depth)-0.57 x 0.74 x 0.24 inches
  • CONVENIENT CONTROLS - Easy-to-reach Back/Forward buttons makes moving quickly between documents or browsing your favorite Web sites a breeze
  • MICRO-PRECISE SCROLL WHEEL - With more grooves per millimeter, our new scroll wheel gives you the ultimate navigation experience
  • LONG BATTERY LIFE - 3 year battery life and smart sleep mode help you go longer between battery changes
Bestseller No. 4
SANWA 2.4G Wireless Ergonomic Mouse, Optical Vertical Mice, for Small Hands, Reduce Wrist Strain, (800/1200/1600 Adjustable DPI, 6 Buttons) Compatible with MacBook, Laptop, Windows, Mac OS, GMAERGW17
  • ERGONOMIC DESIGN - Places your hand in a natural "handshake" wrist & arm position for smoother movement and less muscle tension. Cute Rounded shape just fits in the palm of your hand. Once you get used to it, you will love it!
  • ADJUSTABLE DPI - Switch between DPI levels 800 / 1200 / 1600 to adjust mouse responsiveness depending on your needs. And Blue LED tracking technology, enabling you to use the mouse on a wide range of surfaces.
  • EASIER WEB BROWSING - Advanced "Back" & "Forward" functionality buttons that located near the thumb area will provide convenience when web page browsing. *For Mac series, Forward / Backward buttons will not work.
  • WIDE COMPATIBILITY - Compatible with most system including Windows 10 / 8.1 / 8 / 7, XP, Vista & macOS 10.12~10.14, Mac OS X 10.3~10.11. Fit for Notebook, PC, Laptop, Computer and other device. *Not fully compatible with Apple products.
  • 2.4GHZ WIRELESS - You can enjoy a clutter-free work area! ※Notice: All SANWA Products provide the same high quality after-service as in Japan, including a 1-Year Worry-Free Manufacturer Warranty & free lifetime technical support.※
Bestseller No. 5
Amazon Basics Full-Size Ergonomic Wireless PC Mouse with Fast Scrolling
  • Full-size wireless mouse with fast-scrolling, clickable wheel and forward/back thumb buttons for fast, easy navigating through large documents and web pages
  • Ergonomically designed for right-handed users; smooth, gently curved profile fits perfectly in the palm of the hand for enhanced comfort
  • 2.4 GHz (non-bluetooth) wireless connection; uses a small USB receiver that can stay plugged into your computer without obstructing other ports
  • Optical sensor (1600 DPI resolution) works on most surfaces; uses 2 AA batteries (included); battery LED light and on/off switch for extended battery life
  • Compatible with Windows 7, 8, and 10; backed by an Amazon Basics 1-year limited warranty
Bestseller No. 6
Left Handed Mouse, Lekvey Wireless 2.4G USB Left Hand Ergonomic Vertical Mouse, Less Noise - Black
  • ✔ LEFT-HANDED ERGONOMIC VERTICAL MOUSE -- Specifically-designed for left-handers, encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. Recommended to Repetitive Strain Injuries RSI User and user works particularly long periods on the computer.
  • ✔ EASY TO USE, PLUG & PLAY -- Strong and reliable 2.4GHz wireless connection, one nano USB receiver at the bottom of mouse, just Plug and Play! The left-handed mouse dimensions : 5.0*3.0*2.5 inches. Weight: 95g.【 NOT compatibility with Mac OS】【 Please confirm the size and system before buying it 】
  • ✔ MULTIFUNCTION AND CONVENIENT -- Easy access to multiple usage through 6 buttons. Advanced "Page Back" and "Page Forward" functionality buttons provide convenience when web page browsing. 3-level DPI (800/1200/1600) suit both ordinary and gaming needs, with premium optical engine, allows quicker response, smoother tracking and higher precision movement.
  • ✔ POWER-SAVING MOUSE -- An independent On/Off switch button on the bottom which helps save energy effectively. Besides, it will automatically enter into sleeping mode after 8 minutes idle. Press right or left button for it to wake immediately. ( 2 AAA batteries needed, not included )
  • ✔ WIDE COMPATIBILITY -- This wireless Lekvey Acedada left handed mouse is compatible with Windows 7, 8, 10, XP, 2000, CE, Vista and Linux. Fit for Notebook, PC, Laptop, Computer and other device. ( The USB receiver is at the bottom of the mouse )
SaleBestseller No. 7
Logitech B100 Corded Mouse – Wired USB Mouse for Computers and laptops, for Right or Left Hand Use, Black
  • A comfortable, ambidextrous shape feels good in either hand, so you feel more comfortable as you work-even at the end of the day.
  • With 800 DPI sensitivity, you'll get precise cursor control so you can edit documents and navigate the web more efficiently.
  • Side-to-side scrolling Plus zoom lets you instantly zoom in or out and scroll horizontally and vertically. Perfect for working with spreadsheets and presentations.*
  • Zero setup with flexible connectivity means you just plug it into your USB or PS/2 port-it works right out of the box.
  • This mouse is built by logitech-the mouse experts. It comes with the quality and design We've built into more than a billion mice, more than any other manufacturer.
Bestseller No. 8
Ergonomic Mouse,Unique 33 Degree Vertical Wireless Mouse - 2.4GHz Optical Vertical Mice : 3 Adjustable DPI 800/1200/1600 Levels, for Laptop, PC, Computer,Notebook etc, Right Hand( Medium)
  • [NATURAL HANDSHAKE POSITION] Wireless NEWTRAL Vertical mice has been designed in ergonomic natural handshake position and tested with criteria set out by leading ergonomists – promoting a more ergonomic posture, smoother movement, and lowering muscle strain
  • [33° VERTICAL ANGLE FOR IMPROVED WRIST POSTURE] Unique 33° vertical angle reduces the pressure on your wrist, while your thumb is positioned comfortably on the thumb rest, reducing wrist pressure and hand fatigue by 31%
  • [HIGH RESPONSIVENESS] With 2.4G wireless and 3 levels DPI to change among 800/1200/1600, NEWTRAL provides more sensitivity for smooth and precise tracking on a wide range of surfaces, things can be done quicker with a precision location sensor featuring a convenient click
  • [HIGH COMPATIBILITY] Compatible with Windows 7/8/10/Mac OS/Linux systems. Instantly connect to your Mac Book / iMac , desktop, laptop, PC or other device by USB dongle.NOTE:Backward button invalid with OS system
  • [CUSTOMER SERVICE] 3 year quality guarantee supports replace or refund within warranty as well as lifetime technical support. Any questions in using, please feel free and contact us
SaleBestseller No. 9
Wired Vertical Mouse, Optical Ergonomic Mouse with 4 Adjustable DPI 800/1200/2000/3200, 5 Buttons USB Computer Mouse , Better for Large and Medium Sized Hands
  • 【Ergonomic Design】-Scientific ergonomic design encourages healthy neutral "handshake" wrist and arm positions for smoother movement and less overall strain. (Note: it is a right-handed mouse)
  • 【More Adjustment】-800 / 1200 / 2000 / 3200 DPI Resolution Optical Tracking Technology provides more sensitivity than standard optical mice for smooth and precise tracking on a wide range of surfaces.
  • 【Useful Page Buttons】-Added next/previous buttons provide convenience when webpage browsing; the superior choice for internet surfers, gamers and people who work at length at the computer.
  • 【No Deed for Battery】-Plug and Play mouse with USB 2.0 interface, easy to start to use with standard setting function. High quality rubber coating surface gives it a feel-good touch
  • 【Wide compatibility】-Compatible with Windows 7/8/10 / Vista / XP / 2000, Mac OS, Linux (NOTE: the forward and backward buttons are not recognized on Mac). Plug and play.
Bestseller No. 10
DELUX Left Handed Vertical Mouse, Reduce Hands Strain Rechargeable Silent BT Wireless Ergonomic Mouse with USB Receiver and BT 4.0, 6 Buttons and 4 Gear DPI for Carpal Tunnel(M618ZD-Iron Grey)
  • [Left Hand Vertical Mouse, Mini and exquisite]: Compact mini lefty vertical mouse with natural handshake design, vertical slope design for palm and with skin-friendly material, fit for human hand structure; Concave area for Thumb and little extended bottom edge for the pinky finger, smoother moving and more comfortable grip; Not just mini but ergonomic, reducing hand fatigue caused by long-term use of a traditional mouse, releasing the pressure
  • [Built-in Rechargeable 1000mAh polymer Li-ion Battery]: At a single power charge and with RGB light on, stable use for a week (8 hours/day); With the auto energy-saving sleep mode and RGB light off, normally it could last for a month, and come with Type-C cable
  • [Dual mode connection]: BT 4.0 and 2.4G RF(USB Nano Receiver stored in the mouse bottom), easy shift between BT and 2.4G wireless mode, adapting different using condition
  • [5 Adjustable DPI and RGB Lighting]: 800/1200/1600/2400/4000 5 shift DPI via the DPI button located above the backward button, easy adjustment; Especially it is with RGB lighting (pressing left, right and scroll button simultaneously to turn on/off the light), lights up your working area and offering your marvelous working experience
  • [All DELUX products include 12 months warranty and free lifetime technical support] [Compatibility]: Compatible with Windows 7/8/10/Android, fit for different devices, PC, Laptop, Computer, Notebook, Phone, Macbook(limited supports to Mac, the backward and forward button are not available for Mac and without Mac version driver) etc

What To Look For Choosing The Best Mouse For Big Hands

Before choosing a mouse for big hands, you should take the following considerations into account.

If you have big hands, or are looking for a Mouse Pad that Can’t be classed as a E-ink Mouse, then we would recommend looking at the top five options below! If you’re looking for an all-in-one mouse also please see: Best All-In-One Mouse. 5. The husband’s ofneeful of money and decided to buy a Minnow. It was a great mouse for the money, but it proved difficult to lose track of his hands while using it. 4. We would recommend the best mouse on the market, as it’s able to handle big complexes including Task Switcher, DPI Monitoring, and All-In-One-astical!

Related Frequently Asked Questions

What Mouse Is Best For Big Hands?

If you have large hands, a touch wheel mouse is the best option. They are easy to use and have many options for turboing up your gaming experience.

Does Hand Size Matter For Mouse?

hand size does not matter for mouse

What Is My Hand Size For Mouse?

A mouse is a computer mouse that has a hand.

Is The G203 Good For Big Hands?

The G203 is a great hands-free camera for big people because it can take many temperatures andMany other features like digital audiozoom.

Conclusion

There is no one mouse to choose for anyone if they have big hands. Some of the best mice for big hands to buy include the ones that are designed for right-handers like the F5 or Yameiren 5200, while those that are for left-handers like the W1 or W2050. Finally, find what size Mouse you need and stick with it until your hands disappear into the abyss of perfecting theirination control.